Форум хімфаку КНУ

korendovych

Користувач

Реєстрація: 29.11.2005

К-ть повідомлень: 378

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Postdoctoral Fellowships at MGH

Postdoctoral positions are available at the Martinos Center for Biomedical Imaging at the Department of Radiology, Massachusetts General Hospital, Harvard Medical School. The Martinos Center is equipped with state of the art imaging facilities dedicated to research, including 1.5T, 3T, 7T MRI systems for humans as well as 4.7T, 9.4T, and 14T MRI systems for animal models. The hospital has a cyclotron and hot cells for production of positron emitting probes and micro- and clinical PET/CT scanners for animal and human imaging. The Martinos Center has recently expanded to include new chemistry labs with onsite analytical instrumentation such as solution and solid state NMR, ICP-MS, LC-MS, and time-resolved fluorimetry.

Candidates should have a strong background in synthetic chemistry, a willingness to learn new techniques, and a desire to see their work translated into clinical imaging agents.

Research projects are in the areas of neuroimaging and oncology. Projects involve design and synthesis of new imaging probes that target specific disease states either by binding to a receptor or a protein upregulated in the disease state, or by making the probe sensitive to the physiology of the disease state (pH, oxygenation, permeability, etc). In all cases either an MRI active component (e.g. paramagnetic complex) or a positron emitter (e.g. F-18) is incorporated into a molecule that has specificity for disease. Probes are characterized in vitro with respect to affinity, specificity, and imaging properties (e.g. relaxivity). Promising new probes are employed to characterize in vivo disease state models, and in some instances translated into clinical studies.
This is a multidisciplinary role where the motivated scientist will build on existing expertise and develop new skills. It offers the opportunity to create new imaging agents and evaluate their potential for medical use.
Positions are for 1 year and are renewable. Candidates should hold a PhD in Chemistry or related discipline and a demonstrated ability in some aspect of synthetic chemistry (organic, inorganic, polymer, or radiochemistry). Experience in aqueous coordination chemistry, radiolabeling, bioconjugation techniques, MRI or nuclear imaging is useful, though not essential.

Contact: Peter Caravan, caravan@nmr.mgh.harvard.edu

The Massachusetts General Hospital is an Equal Opportunity/Affirmative Action Employer.

Відредаговано korendovych (06.04.2007 21:39:36)

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Physics is like sex: sure, it may give some practical results, but that's not why we do it.

                                                                                                       Richard Feynman